Vasoactive Intestinal Peptide Modulation of the Steroid-Induced LH Surge Involves Kisspeptin Signaling in Young but Not in Middle-Aged Female Rats

Age-related LH surge dysfunction in middle-aged rats is characterized, in part, by reduced responsiveness to estradiol (E2)-positive feedback and reduced hypothalamic kisspeptin neurotransmission. Vasoactive intestinal peptide (VIP) neurons in the suprachiasmatic nucleus project to hypothalamic regi...

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Hauptverfasser: Kauffman, Alexander S., Sun, Yan, Kim, Joshua, Khan, Azim R., Shu, Jun, Neal-Perry, Genevieve
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2014
Schlagworte:
Neuroendocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020928/
https://ncbi.nlm.nih.gov/pubmed/24654782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1793
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