Age-related LH surge dysfunction correlates with reduced responsiveness of hypothalamic anteroventral periventricular nucleus kisspeptin neurons to estradiol positive feedback in middle-aged rats

Female reproductive aging in rats is characterized by reduced gonadotropin releasing hormone (GnRH) neuronal activation under estradiol positive feedback conditions and a delayed and attenuated luteinizing hormone (LH) surge. The newly identified excitatory neuropeptide kisspeptin is proposed to be...

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Библиографические подробности
Главные авторы: Lederman, Matthew A., Lebesgue, Diane, Gonzalez, Veronica V., Shu, Jun, Merhi, Zaher O., Etgen, Anne M., Neal-Perry, Genevieve
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901500/
https://ncbi.nlm.nih.gov/pubmed/19559035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.06.015
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