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Evidence That the LH Surge in Ewes Involves Both Neurokinin B–Dependent and –Independent Actions of Kisspeptin

Recent evidence has implicated neurokinin B (NKB) signaling in the retrochiasmatic area (RCh) of the ewe in the LH surge. To test this hypothesis, we first lesioned NK3R neurons in this area by using a saporin conjugate (NK3-SAP). Three weeks after bilateral injection of NK3-SAP or a blank control (...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Goodman, Robert L, He, Wen, Lopez, Justin A, Bedenbaugh, Michelle N, McCosh, Richard B, Bowdridge, Elizabeth C, Coolen, Lique M, Lehman, Michael N, Hileman, Stanley M
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857763/
https://ncbi.nlm.nih.gov/pubmed/31599937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00597
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