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Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering

Small proteins like amyloid beta (Aβ) monomers are related to neurodegenerative disorders by aggregation to insoluble fibrils. Small angle neutron scattering (SANS) is a nondestructive method to observe the aggregation process in solution. We show that SANS is able to resolve monomers of small molec...

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發表在:PLoS One
Main Authors: Zhang-Haagen, Bo, Biehl, Ralf, Nagel-Steger, Luitgard, Radulescu, Aurel, Richter, Dieter, Willbold, Dieter
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769228/
https://ncbi.nlm.nih.gov/pubmed/26919121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150267
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