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Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering

Small proteins like amyloid beta (Aβ) monomers are related to neurodegenerative disorders by aggregation to insoluble fibrils. Small angle neutron scattering (SANS) is a nondestructive method to observe the aggregation process in solution. We show that SANS is able to resolve monomers of small molec...

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Veröffentlicht in:PLoS One
Hauptverfasser: Zhang-Haagen, Bo, Biehl, Ralf, Nagel-Steger, Luitgard, Radulescu, Aurel, Richter, Dieter, Willbold, Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769228/
https://ncbi.nlm.nih.gov/pubmed/26919121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150267
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