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Stepwise nucleosome translocation by RSC remodeling complexes

The SWI/SNF-family remodelers regulate chromatin structure by coupling the free energy from ATP hydrolysis to the repositioning and restructuring of nucleosomes, but how the ATPase activity of these enzymes drives the motion of DNA across the nucleosome remains unclear. Here, we used single-molecule...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Harada, Bryan T, Hwang, William L, Deindl, Sebastian, Chatterjee, Nilanjana, Bartholomew, Blaine, Zhuang, Xiaowei
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769157/
https://ncbi.nlm.nih.gov/pubmed/26895087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10051
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