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ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps
ISWI-family enzymes remodel chromatin by sliding nucleosomes along DNA, but the nucleosome translocation mechanism remains unclear. Here we use single-molecule FRET to probe nucleosome translocation by ISWI-family remodelers. Distinct ISWI-family members translocate nucleosomes with a similar steppi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647478/ https://ncbi.nlm.nih.gov/pubmed/23374341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.040 |
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