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Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains
The ISWI family of ATP-dependent chromatin remodelers represses transcription by changing nucleosome positioning. The interactions with extranucleosomal DNA and the requirement of a minimal length of extranucleosomal DNA by ISWI mediate the spacing of nucleosomes. ISW2 from Saccharomyces cerevisiae,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565048/ https://ncbi.nlm.nih.gov/pubmed/23334290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2486 |
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