ESI-IMS–MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules

Electrospray ionisation-ion mobility spectrometry–mass spectrometry (ESI-IMS–MS) is a powerful method for the study of conformational changes in protein complexes, including oligomeric species populated during protein self-aggregation into amyloid fibrils. Information on the mass, stability, cross-s...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Young, Lydia M., Saunders, Janet C., Mahood, Rachel A., Revill, Charlotte H., Foster, Richard J., Ashcroft, Alison E., Radford, Sheena E.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769093/
https://ncbi.nlm.nih.gov/pubmed/26007606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2015.05.017
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