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A Simple Model to Study Tau Pathology

Tau proteins play a role in the stabilization of microtubules, but in pathological conditions, tauopathies, tau is modified by phosphorylation and can aggregate into aberrant aggregates. These aggregates could be toxic to cells, and different cell models have been used to test for compounds that mig...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Neurosci
Hauptverfasser: Houck, Alexander L., Hernández, Félix, Ávila, Jesús
Format: Artigo
Sprache:Inglês
Veröffentlicht: Libertas Academica 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768941/
https://ncbi.nlm.nih.gov/pubmed/26949341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/JEN.S25100
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