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A Simple Model to Study Tau Pathology

Tau proteins play a role in the stabilization of microtubules, but in pathological conditions, tauopathies, tau is modified by phosphorylation and can aggregate into aberrant aggregates. These aggregates could be toxic to cells, and different cell models have been used to test for compounds that mig...

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Detalhes bibliográficos
Publicado no:J Exp Neurosci
Main Authors: Houck, Alexander L., Hernández, Félix, Ávila, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768941/
https://ncbi.nlm.nih.gov/pubmed/26949341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/JEN.S25100
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