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The role of extracellular Tau in the spreading of neurofibrillary pathology

The microtubule-associated protein (MAP) tau plays a critical role in the pathogenesis of Alzheimer’s disease (AD) and several related disorders collectively known as tauopathies. Development of tau pathology is associated with progressive neuronal loss and cognitive decline. In the brains of AD pat...

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Bibliografiska uppgifter
Huvudupphovsmän: Medina, Miguel, Avila, Jesús
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005959/
https://ncbi.nlm.nih.gov/pubmed/24795568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00113
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