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The role of extracellular Tau in the spreading of neurofibrillary pathology

The microtubule-associated protein (MAP) tau plays a critical role in the pathogenesis of Alzheimer’s disease (AD) and several related disorders collectively known as tauopathies. Development of tau pathology is associated with progressive neuronal loss and cognitive decline. In the brains of AD pat...

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Detalhes bibliográficos
Main Authors: Medina, Miguel, Avila, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005959/
https://ncbi.nlm.nih.gov/pubmed/24795568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00113
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