Knockout mouse production assisted by Blm knockdown

Production of knockout mice using targeted embryonic stem cells (ESCs) is a powerful approach for investigating the function of specific genes in vivo. Although the protocol for gene targeting via homologous recombination (HR) in ESCs is already well established, the targeting efficiency varies at d...

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Bibliographische Detailangaben
Veröffentlicht in:J Reprod Dev
Hauptverfasser: FUKUDA, Mikiko, INOUE, Mayuko, MURAMATSU, Daisuke, MIYACHI, Hitoshi, SHINKAI, Yoichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Society for Reproduction and Development 2015
Schlagworte:
Technology Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768786/
https://ncbi.nlm.nih.gov/pubmed/26598326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2015-122
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