Hepatocyte FRS2α is Essential for the Endocrine Fibroblast Growth Factor to Limit the Amplitude of Bile Acid Production Induced by Prandial Activity

In addition to being positively regulated by prandial activity, bile acid production is also negatively controlled by the endocrine fibroblast growth factor 19 (FGF19) or the mouse ortholog FGF15 from the ileum that represses hepatic cholesterol 7 α-hydroxylase (Cyp7a1) expression through activating...

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發表在:Curr Mol Med
Main Authors: Wang, Cong, Yang, Chaofeng, Chang, Julia YF, You, Pan, Li, Yue, Jin, Chengliu, Luo, Yongde, Li, Xiaokun, McKeehan, Wallace L., Wang, Fen
格式: Artigo
語言:Inglês
出版: 2014
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768716/
https://ncbi.nlm.nih.gov/pubmed/25056539
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