Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress

BACKGROUND: Endocrine FGF19 and FGF21 exert their effects on metabolic homeostasis through fibroblast growth factor receptor (FGFR) and co-factor betaKlotho (KLB). Ileal FGF19 regulates bile acid metabolism through specifically FGFR4-KLB in hepatocytes where FGFR1 is not significant. Both FGF19 and...

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Bibliografiske detaljer
Main Authors: Yang, Chaofeng, Wang, Cong, Ye, Min, Jin, Chengliu, He, Weimin, Wang, Fen, McKeehan, Wallace L, Luo, Yongde
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545967/
https://ncbi.nlm.nih.gov/pubmed/23106963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-9-94
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