A Multi‐RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs

Packaging multiple small interfering RNA (siRNA) molecules into nanostructures at precisely defined ratios is a powerful delivery strategy for effective RNA interference (RNAi) therapy. We present a novel RNA nanotechnology based approach to produce multiple components of polymerized siRNA molecules...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Roh, Young Hoon, Deng, Jason Z., Dreaden, Erik C., Park, Jae Hyon, Yun, Dong Soo, Shopsowitz, Kevin E., Hammond, Paula T.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768639/
https://ncbi.nlm.nih.gov/pubmed/26695874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201508978
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