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Intravenous immune globulin suppresses angiogenesis in mice and humans

Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are incompletely understood and have been attributed both to the polyclo...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Yasuma, Reo, Cicatiello, Valeria, Mizutani, Takeshi, Tudisco, Laura, Kim, Younghee, Tarallo, Valeria, Bogdanovich, Sasha, Hirano, Yoshio, Kerur, Nagaraj, Li, Shengjian, Yasuma, Tetsuhiro, Fowler, Benjamin J, Wright, Charles B, Apicella, Ivana, Greco, Adelaide, Brunetti, Arturo, Ambati, Balamurali K, Helmers, Sevim Barbasso, Lundberg, Ingrid E, Viklicky, Ondrej, Leusen, Jeanette HW, Verbeek, J Sjef, Gelfand, Bradley D, Bastos-Carvalho, Ana, De Falco, Sandro, Ambati, Jayakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768485/
https://ncbi.nlm.nih.gov/pubmed/26925256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2015.2
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