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Quantifying Lgr5-positive stem cell behaviour in the pyloric epithelium

Using in-vivo lineage tracing data we quantified clonal expansion as well as proliferation and differentiation of the Lgr5-positive stem cell population in pyloric gastric glands. Fitting clone expansion models, we estimated that there are five effective Lgr5-positive cells able to give rise to mono...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leushacke, Marc, Barker, Nick, Pin, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768140/
https://ncbi.nlm.nih.gov/pubmed/26916214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21923
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