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Mechanical Conflict System: A Novel Operant Method for the Assessment of Nociceptive Behavior

A new operant test for preclinical pain research, termed the Mechanical Conflict System (MCS), is presented. Rats were given a choice either to remain in a brightly lit compartment or to escape to a dark compartment by crossing an array of height-adjustable nociceptive probes. Latency to escape the...

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Publicado en:PLoS One
Autores principales: Harte, Steven E., Meyers, Jessica B., Donahue, Renee R., Taylor, Bradley K., Morrow, Thomas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767889/
https://ncbi.nlm.nih.gov/pubmed/26915030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150164
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