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Use of the Operant Orofacial Pain Assessment Device (OPAD) to Measure Changes in Nociceptive Behavior

We present an operant system for the detection of pain in awake, conscious rodents. The Orofacial Pain Assessment Device (OPAD) assesses pain behaviors in a more clinically relevant way by not relying on reflex-based measures of nociception. Food fasted, hairless (or shaved) rodents are placed into...

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Autori principali: Anderson, Ethan M., Mills, Richard, Nolan, Todd A., Jenkins, Alan C., Mustafa, Golam, Lloyd, Chris, Caudle, Robert M., Neubert, John K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727247/
https://ncbi.nlm.nih.gov/pubmed/23792907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50336
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