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The Effects of a Co-Application of Menthol and Capsaicin on Nociceptive Behaviors of the Rat on the Operant Orofacial Pain Assessment Device

BACKGROUND: Transient receptor potential (TRP) cation channels are involved in the perception of hot and cold pain and are targets for pain relief in humans. We hypothesized that agonists of TRPV1 and TRPM8/TRPA1, capsaicin and menthol, would alter nociceptive behaviors in the rat, but their opposit...

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Detalhes bibliográficos
Main Authors: Anderson, Ethan M., Jenkins, Alan C., Caudle, Robert M., Neubert, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928399/
https://ncbi.nlm.nih.gov/pubmed/24558480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089137
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