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Use of the Operant Orofacial Pain Assessment Device (OPAD) to Measure Changes in Nociceptive Behavior

We present an operant system for the detection of pain in awake, conscious rodents. The Orofacial Pain Assessment Device (OPAD) assesses pain behaviors in a more clinically relevant way by not relying on reflex-based measures of nociception. Food fasted, hairless (or shaved) rodents are placed into...

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Autors principals: Anderson, Ethan M., Mills, Richard, Nolan, Todd A., Jenkins, Alan C., Mustafa, Golam, Lloyd, Chris, Caudle, Robert M., Neubert, John K.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727247/
https://ncbi.nlm.nih.gov/pubmed/23792907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50336
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