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Phosphate–Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1

Tubulo-interstitial fibrosis is a common, destructive endpoint for a variety of kidney diseases. Fibrosis is well correlated with the loss of kidney function in both humans and rodents. The identification of modulators of fibrosis could provide novel therapeutic approaches to reducing disease progre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shen, Zhong-Jian, Hu, Jie, Shiizaki, Kazuhiro, Kuro-o, Makoto, Malter, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767802/
https://ncbi.nlm.nih.gov/pubmed/26914452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150093
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