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Phosphate–Induced Renal Fibrosis Requires the Prolyl Isomerase Pin1

Tubulo-interstitial fibrosis is a common, destructive endpoint for a variety of kidney diseases. Fibrosis is well correlated with the loss of kidney function in both humans and rodents. The identification of modulators of fibrosis could provide novel therapeutic approaches to reducing disease progre...

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Publicat a:PLoS One
Autors principals: Shen, Zhong-Jian, Hu, Jie, Shiizaki, Kazuhiro, Kuro-o, Makoto, Malter, James S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767802/
https://ncbi.nlm.nih.gov/pubmed/26914452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150093
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