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TLR-7 stress signaling in differentiating and mature eosinophils is mediated by the prolyl isomerase Pin1

The response of eosinophils to respiratory virus has emerged as an important link between pulmonary infection and allergic asthmatic exacerbations. Eosinophils activate innate immune responses through toll-like receptor (TLR) signaling. Here, using mouse and human eosinophils and mice lacking the pr...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Shen, Zhong-Jian, Hu, Jie, Kashi, Venkatesh, Bochkov, Yury A, Gern, James E., Malter, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909928/
https://ncbi.nlm.nih.gov/pubmed/30397031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800881
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