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Comparison of Design Strategies for α-Helix Backbone Modification in a Protein Tertiary Fold()
We report here the comparison of five classes of unnatural amino acid building blocks for their ability to be accommodated into an α-helix in a protein tertiary fold context. High-resolution structural characterization and analysis of folding thermodynamics yield new insights into the relationship b...
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| Publicado en: | Chem Commun (Camb) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767680/ https://ncbi.nlm.nih.gov/pubmed/26853882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc00273k |
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