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Comparison of Design Strategies for α-Helix Backbone Modification in a Protein Tertiary Fold()

We report here the comparison of five classes of unnatural amino acid building blocks for their ability to be accommodated into an α-helix in a protein tertiary fold context. High-resolution structural characterization and analysis of folding thermodynamics yield new insights into the relationship b...

詳細記述

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書誌詳細
出版年:Chem Commun (Camb)
主要な著者: Tavenor, Nathan A., Reinert, Zachary E., Lengyel, George A., Griffith, Brian D., Horne, W. Seth
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767680/
https://ncbi.nlm.nih.gov/pubmed/26853882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc00273k
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