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Protein Backbone Engineering as a Strategy to Advance Foldamers toward the Frontier of Protein-Like Tertiary Structure
A variety of non-biological structural motifs have been incorporated into the backbone of natural protein sequences. In parallel work, diverse unnatural oligomers of de novo design (termed “foldamers”) have been developed that fold in defined ways. In this Perspective article, we survey foundational...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4211622/ https://ncbi.nlm.nih.gov/pubmed/25285575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01769b |
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