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FGFR and PTEN signaling interact during lens development to regulate cell survival
Lens epithelial cells express many receptor tyrosine kinases (RTKs) that stimulate PI3K-AKT and RAS-RAF-MEK-ERK intracellular signaling pathways. These pathways ultimately activate the phosphorylation of key cellular transcription factors and other proteins that control proliferation, survival, meta...
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| Veröffentlicht in: | Dev Biol |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767529/ https://ncbi.nlm.nih.gov/pubmed/26764128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.12.027 |
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