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Conformational Heterogeneity of the SAM-I Riboswitch Transcriptional ON State: A Chaperone-like Role for S-adenosylmethionine

Riboswitches are promising targets for the design of novel antibiotics and engineering of portable genetic regulatory elements. There is evidence that variability in riboswitch properties allows tuning of expression for genes involved in different stages of biosynthetic pathways by mechanisms that a...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Huang, Wei, Kim, Joohyun, Jha, Shantenu, Aboul-ela, Fareed
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767528/
https://ncbi.nlm.nih.gov/pubmed/22425639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.019
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