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A mechanism for S-adenosyl methionine assisted formation of a riboswitch conformation: a small molecule with a strong arm

The S-adenosylmethionine-1 (SAM-I) riboswitch mediates expression of proteins involved in sulfur metabolism via formation of alternative conformations in response to binding by SAM. Models for kinetic trapping of the RNA in the bound conformation require annealing of nonadjacent mRNA segments during...

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Bibliografiske detaljer
Main Authors: Huang, Wei, Kim, Joohyun, Jha, Shantenu, Aboul-ela, Fareed
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770654/
https://ncbi.nlm.nih.gov/pubmed/19720737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp664
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