Single-molecule chemical denaturation of riboswitches

To date, single-molecule RNA science has been developed almost exclusively around the effect of metal ions as folding promoters and stabilizers of the RNA structure. Here, we introduce a novel strategy that combines single-molecule Förster resonance energy transfer (FRET) and chemical denaturation t...

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Bibliographic Details
Main Authors: Dalgarno, Paul A., Bordello, Jorge, Morris, Rhodri, St-Pierre, Patrick, Dubé, Audrey, Samuel, Ifor D. W., Lafontaine, Daniel A., Penedo, J. Carlos
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627600/
https://ncbi.nlm.nih.gov/pubmed/23446276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt128
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