Unprecedented tunability of riboswitch structure and regulatory function by sub-millimolar variations in physiological Mg(2+)

Riboswitches are cis-acting regulatory RNA biosensors that rival the efficiency of those found in proteins. At the heart of their regulatory function is the formation of a highly specific aptamer–ligand complex. Understanding how these RNAs recognize the ligand to regulate gene expression at physiol...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: McCluskey, Kaley, Boudreault, Julien, St-Pierre, Patrick, Perez-Gonzalez, Cibran, Chauvier, Adrien, Rizzi, Adrien, Beauregard, Pascale B, Lafontaine, Daniel A, Penedo, J Carlos
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
RNA and RNA-protein complexes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614840/
https://ncbi.nlm.nih.gov/pubmed/31045204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz316
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