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Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB

An intriguing biological question relating to cell signaling is how the inflammatory mediator NF-kB and the tumour suppressor protein p53 can be induced by similar triggers, like DNA damage or infection, yet have seemingly opposing or sometimes cooperative biological functions. For example, the NF-κ...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Hu, Ying, Ge, Wenjie, Wang, Xingwen, Sutendra, Gopinath, Zhao, Kunming, Dedeić, Zinaida, Slee, Elizabeth A., Baer, Caroline, Lu, Xin
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767446/
https://ncbi.nlm.nih.gov/pubmed/26646590
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