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Nuclear iASPP determines cell fate by selectively inhibiting either p53 or NF-κB
p53 and NF-κBp65 are essential transcription factors (TFs) in the cellular response to stress. Two signaling systems can often be entwined together and generally produce opposing biological outcomes in a cell context-dependent manner. Inhibitor of apoptosis-stimulating protein of p53 (iASPP) has the...
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| Pubblicato in: | Cell Death Discov |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8313550/ https://ncbi.nlm.nih.gov/pubmed/34312379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00582-1 |
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