In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection

Persistent hepatitis B virus (HBV) infection is established by the formation of an intranuclear pool of covalently closed circular DNA (cccDNA) in the liver. Very little is known about the intrahepatic distribution of HBV cccDNA in infected patients, particularly at the single-cell level. Here, we e...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Zhang, Xiaonan, Lu, Wei, Zheng, Ye, Wang, Weixia, Bai, Lu, Chen, Liang, Feng, Yanling, Zhang, Zhanqing, Yuan, Zhenghong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767362/
https://ncbi.nlm.nih.gov/pubmed/26901811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83339
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