Extracellular Hepatitis B Virus RNAs Are Heterogeneous in Length and Circulate as Capsid-Antibody Complexes in Addition to Virions in Chronic Hepatitis B Patients

Extracellular HBV RNA has been detected in both HBV-replicating cell culture media and sera from chronic hepatitis B (CHB) patients, but its exact origin and composition remain controversial. Here, we demonstrated that extracellular HBV RNA species were of heterogeneous lengths, ranging from the len...

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Pubblicato in:J Virol
Autori principali: Bai, Lu, Zhang, Xiaonan, Kozlowski, Maya, Li, Weixia, Wu, Min, Liu, Jiangxia, Chen, Liang, Zhang, Jiming, Huang, Yuxian, Yuan, Zhenghong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258948/
https://ncbi.nlm.nih.gov/pubmed/30282709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00798-18
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