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In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection

Persistent hepatitis B virus (HBV) infection is established by the formation of an intranuclear pool of covalently closed circular DNA (cccDNA) in the liver. Very little is known about the intrahepatic distribution of HBV cccDNA in infected patients, particularly at the single-cell level. Here, we e...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhang, Xiaonan, Lu, Wei, Zheng, Ye, Wang, Weixia, Bai, Lu, Chen, Liang, Feng, Yanling, Zhang, Zhanqing, Yuan, Zhenghong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767362/
https://ncbi.nlm.nih.gov/pubmed/26901811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83339
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