Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma

Melanoma prognosis is dictated by tumor-infiltrating lymphocytes, the migratory and functional behavior of which is guided by chemokine or cytokine gradients. Here, we retrospectively analyzed the expression patterns of 9 homing receptors (CCR/CXCR) in naive and memory CD4(+) and CD8(+) T lymphocyte...

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Vydáno v:J Clin Invest
Hlavní autoři: Jacquelot, Nicolas, Enot, David P., Flament, Caroline, Vimond, Nadège, Blattner, Carolin, Pitt, Jonathan M., Yamazaki, Takahiro, Roberti, María Paula, Daillère, Romain, Vétizou, Marie, Poirier-Colame, Vichnou, Semeraro, Michaëla, Caignard, Anne, Slingluff, Craig L., Sallusto, Federica, Rusakiewicz, Sylvie, Weide, Benjamin, Marabelle, Aurélien, Kohrt, Holbrook, Dalle, Stéphane, Cavalcanti, Andréa, Kroemer, Guido, Di Giacomo, Anna Maria, Maio, Michele, Wong, Phillip, Yuan, Jianda, Wolchok, Jedd, Umansky, Viktor, Eggermont, Alexander, Zitvogel, Laurence
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767356/
https://ncbi.nlm.nih.gov/pubmed/26854930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80071
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