Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma

Melanoma prognosis is dictated by tumor-infiltrating lymphocytes, the migratory and functional behavior of which is guided by chemokine or cytokine gradients. Here, we retrospectively analyzed the expression patterns of 9 homing receptors (CCR/CXCR) in naive and memory CD4(+) and CD8(+) T lymphocyte...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Jacquelot, Nicolas, Enot, David P., Flament, Caroline, Vimond, Nadège, Blattner, Carolin, Pitt, Jonathan M., Yamazaki, Takahiro, Roberti, María Paula, Daillère, Romain, Vétizou, Marie, Poirier-Colame, Vichnou, Semeraro, Michaëla, Caignard, Anne, Slingluff, Craig L., Sallusto, Federica, Rusakiewicz, Sylvie, Weide, Benjamin, Marabelle, Aurélien, Kohrt, Holbrook, Dalle, Stéphane, Cavalcanti, Andréa, Kroemer, Guido, Di Giacomo, Anna Maria, Maio, Michele, Wong, Phillip, Yuan, Jianda, Wolchok, Jedd, Umansky, Viktor, Eggermont, Alexander, Zitvogel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767356/
https://ncbi.nlm.nih.gov/pubmed/26854930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80071
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