Breaking the dogma: PCB-derived semiquinone free radicals do not form covalent adducts with DNA, GSH, and amino acids

Covalent bond formations of free radical metabolites with biomolecules like DNA and proteins are thought to constitute a major mechanism of toxicity and carcinogenesis. Glutathione (GSH) is generally accepted as a radical scavenger protecting the cell. In the present study, we investigated a semiqui...

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Detaylı Bibliyografya
Yayımlandı:Environ Sci Pollut Res Int
Asıl Yazarlar: Wangpradit, Orarat, Rahaman, Asif, Mariappan, S. V. Santhana, Buettner, Garry R., Robertson, Larry W., Luthe, Gregor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767158/
https://ncbi.nlm.nih.gov/pubmed/26396011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11356-015-5007-4
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