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Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase

Hormonally–sensitive tissues, like the prostate, ovary and breast, increasingly studied as targets of environmental chemicals, are sources of an enzyme potentially capable of transforming and activating xenobiotics to highly reactive metabolites. Our study specifically addresses the question of whet...

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Autors principals: Wangpradit, Orarat, Teesch, Lynn M, Mariappan, S. V. Santhana, Duffel, Michael W, Norstrom, Karin, Robertson, Larry W, Luthe, Gregor
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637223/
https://ncbi.nlm.nih.gov/pubmed/19105592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800300t
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