Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux

Studies in lipoprotein kinetics almost exclusively rely on steady-state approaches to modeling. Herein, we have used a non-steady-state experimental design to examine the role of cholesteryl ester transfer protein (CETP) in mediating HDL-TG flux in vivo in rhesus macaques, and therefore, we develope...

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Vydáno v:J Lipid Res
Hlavní autoři: McLaren, David G., Previs, Stephen F., Phair, Robert D., Stout, Steven J., Xie, Dan, Chen, Ying, Salituro, Gino M., Xu, Suoyu S., Castro-Perez, Jose M., Opiteck, Gregory J., Akinsanya, Karen O., Cleary, Michele A., Dansky, Hayes M., Johns, Douglas G., Roddy, Thomas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766989/
https://ncbi.nlm.nih.gov/pubmed/26658238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M063842
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