CRL2 Aids Elimination of Truncated Selenoproteins Produced by Failed UGA/Sec Decoding

Selenocysteine (Sec) is translated from the codon UGA, typically a termination signal. Codon duality extends the genetic code; coexistence of two competing UGA-decoding mechanisms, however, immediately compromises proteome fidelity. Selenium availability tunes reassignment of UGA to Sec. We report a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Science
Huvudupphovsmän: Lin, Hsiu-Chuan, Ho, Szu-Chi, Chen, Yi-Yun, Khoo, Kay-Hooi, Hsu, Pang-Hung, Yen, Hsueh-Chi S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766860/
https://ncbi.nlm.nih.gov/pubmed/26138980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab0515
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk