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Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and NFκB in rodent diabetic liver and relationships to hyperlipidemia and insulin resistance
Previous findings in diabetic rodents suggest that insulin activation of atypical protein kinase C (aPKC) is impaired in muscle, but surprisingly conserved in liver, despite impaired hepatic PKB/Akt activation. Moreover, aPKC at least partly regulates two major trans-activators, viz.,hepatic sterol...
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| I publikationen: | Diabetologia |
|---|---|
| Huvudupphovsmän: | , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4766834/ https://ncbi.nlm.nih.gov/pubmed/19357831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-009-1336-5 |
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