Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

BACKGROUND: Osteoporosis is a common and debilitating bone disease that is characterised by a low bone mineral density (BMD), a highly heritable trait. Genome-wide association studies (GWAS) have proven to be very successful in identifying common genetic variants associated with BMD adjusted for age...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Mullin, Benjamin H., Walsh, John P., Zheng, Hou-Feng, Brown, Suzanne J., Surdulescu, Gabriela L., Curtis, Charles, Breen, Gerome, Dudbridge, Frank, Richards, J. Brent, Spector, Tim D., Wilson, Scott G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766752/
https://ncbi.nlm.nih.gov/pubmed/26911590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2481-0
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