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Hemoglobin induced NO/cGMP suppression Deteriorate Microcirculation via Pericyte Phenotype Transformation after Subarachnoid Hemorrhage in Rats

Subarachnoid hemorrhage (SAH) usually results from ruptured aneurysm, but how leaked hemoglobin regulates the microcirculation in the pathophysiology of early brain injury after SAH is still unclear. In the present study, we sought to investigate the role and possible mechanism of hemoglobin induced...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Li, Qiang, Chen, Yujie, Li, Bo, Luo, Chunxia, Zuo, Shilun, Liu, Xin, Zhang, John H., Ruan, Huaizhen, Feng, Hua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766506/
https://ncbi.nlm.nih.gov/pubmed/26911739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22070
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