Hemoglobin induced NO/cGMP suppression Deteriorate Microcirculation via Pericyte Phenotype Transformation after Subarachnoid Hemorrhage in Rats

Subarachnoid hemorrhage (SAH) usually results from ruptured aneurysm, but how leaked hemoglobin regulates the microcirculation in the pathophysiology of early brain injury after SAH is still unclear. In the present study, we sought to investigate the role and possible mechanism of hemoglobin induced...

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Vydáno v:Sci Rep
Hlavní autoři: Li, Qiang, Chen, Yujie, Li, Bo, Luo, Chunxia, Zuo, Shilun, Liu, Xin, Zhang, John H., Ruan, Huaizhen, Feng, Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766506/
https://ncbi.nlm.nih.gov/pubmed/26911739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22070
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