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Conditional Disabled-1 Deletion in Mice Alters Hippocampal Neurogenesis and Reduces Seizure Threshold

Many animal models of temporal lobe epilepsy (TLE) exhibit altered neurogenesis arising from progenitors within the dentate gyrus subgranular zone (SGZ). Aberrant integration of new neurons into the existing circuit is thought to contribute to epileptogenesis. In particular, adult-born neurons that...

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Bibliografiske detaljer
Udgivet i:Front Neurosci
Main Authors: Korn, Matthew J., Mandle, Quinton J., Parent, Jack M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766299/
https://ncbi.nlm.nih.gov/pubmed/26941603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00063
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